Harvard University

PhD, 2016, Biological and Biomedical Sciences

Massachusetts Institute of Technology

BS, 2009, Biological Engineering

Ekaterina Pak

Staff Scientist

t 617-248-4724   f 617-502-4724

Dr. Ekaterina Pak utilizes her biological expertise to provide maximum results for her clients.

Practice Focus

Intellectual Property: assists in the preparation and prosecution of patent applications. Also assists with freedom-to-operate analysis, due diligence reviews, infringement opinions and invalidity analysis.   Dr. Pak’s work covers technologies including antibodies, small molecules, peptides, pharmaceutical formulations, methods of treatment using pharmaceutical compositions, biomarkers, gene therapy vectors, antibody production and purification, RNA interference and in vitro expression systems.

Previous Experience

Prior to joining Choate, Dr. Pak drafted early commercialization assessments for emerging biomedical technologies, investigated prior art and patent landscape for IP development and surveyed market size, commercial value, and competing interests in related fields at Harvard University.

Representative Engagements

  • Assisted in preparing and prosecuting patent applications for biomedical companies and research institutions, including applications for protecting antibodies and corresponding uses.
  • Assisted in due diligence and freedom to operate analysis for academic and industrial clients.
  • Conducted prior art and patent landscape searches for gene therapy, cancer immunotherapy, and commercial production of extracted biologic materials.

Publications and Presentations

  • “Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy,” first author, Dev. Cell., 2016.
  • “RAS/MAPK activation drives resistance to Smo inhibition, metastasis, and tumor evolution in Shh pathway-dependent tumors,” co-author, Cancer Res., 2015.
  • “New progenitors NESTIN(g)” in the EGL. Co-author, Neurosci. 2013.
  • “Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities,” co-author, Nat. Med., 2013.

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