Education

Northeastern University
PhD, 2013, Chemistry/Biochemistry

Rochester Institute of Technology
BS, 2008,  Chemistry, Minor in Criminal  Justice

Practice Areas

Lisa A. Hawver, PhD

Staff Scientist

t 617-248-4797   f 617-502-4797

Lisa Hawver is a multi-faceted scientist with over 10 years of experience in chemistry, biochemistry, and microbiology, which she gained through research experience at Rochester Institute of Technology, Northeastern University, and Tufts University. Lisa uses her scientific knowledge to help clients obtain worldwide protection for their biological inventions.

Practice Focus

Intellectual Property: assists in the preparation and prosecution of patent applications, as well as freedom-to-operate and patentability analyses. Dr. Hawver’s work covers technologies including antibodies, small molecules, peptides, pharmaceutical formulations, methods of treatment using pharmaceutical compositions, biomarkers, gene therapy vectors, antibody production and purification, RNA interference and in vitro expression systems, and genetically engineered organisms.

Previous Experience

Dr. Hawver earned her Ph.D. at Northeastern University, under the guidance of Dr. Penny Beuning. Her graduate research was focused on characterizing the active site and other important residues for specificity of an E. coli Y Family DNA Polymerase called Pol V. Her subsequent postdoctoral work under Dr. Wai-Leung Ng at Tufts University was focused on investigating the functions of small RNAs in Vibrio cholerae, with a focus on understanding how these small RNAs regulate metabolic processes to maintain population stability via quorum sensing. While at Tufts University, Dr. Hawver was an intern at the technology transfer office where she receiving hands-on training regarding the evaluation of invention disclosures, patent protection, market analysis, and drafting and negotiating research and license agreements in relation to technologies developed at the university.

Representative Engagements

  • Assisted in preparing and prosecuting patent applications for biomedical companies and research institutions, including applications for protecting antibodies and corresponding uses, protein formulations, pharmaceutical regimens and uses, and genetically engineered organisms.
  • Assisted in due diligence and freedom to operate analysis for academic and industrial clients on subject matter including gene therapy vectors and protein formulations.
  • Conducted prior art and patent landscape searches for biotechnology companies on subject matter including oils produced by microbes.
  • Drafted Third Party Submissions challenging claims directed to antibodies.

Publications

  • “Quorum-sensing coordinates cooperative expression of pyruvate metabolism genes to maintain a sustainable environment for population stability,” co-author, MBio, 2016.
  • “Specificity and Complexity in Bacterial Quorum Sensing Systems,” co-author, FEMS Microbiology Reviews, 2016.
  • “Parallel quorum sensing signaling pathways in Vibrio Cholerae,” co-author, Current Genetics, 2015.
  • “Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions," co-author, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2015.
  • "Chapter 486 UmuC D Lesion Bypass DNA Polymerase V" Encyclopaedia of Biological Chemistry 2nd edition. W. J. Lennarz and M. D. Lane, Eds., Elsevier Science, co-author, 2013.
  • “Characterization of Escherichia coli UmuC Active Site Loop Variants that Confer UV Hypersensitivity” Journal of Bacteriology, co-author, 2011.
  • "Escherichia coli Y Family DNA Polymerases" Frontiers in Bioscience, co-author, 2011.

Professional and Community Involvement

Dr. Hawver was the founding member of the Science Outreach Committee in the Tufts Postdoctoral Association and was Co-chair of the Tufts Postdoctoral Association Career Development Committee. Lisa enjoys engaging in science outreach in the community, and she has helped organize events and activities for the annual Cambridge Science Festival and the annual Museum of Science Health Fair. Lisa has served as a mentor for the Association for Women in Science.

 

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