Dr. Ellen Corcoran assists Choate’s life sciences clients by utilizing her background in molecular biophysics and biochemistry to help with the preparation and prosecution of patent applications, as well as freedom-to-operate and patentability analyses. Publications and Presentations “Autoinhibition of the GEF activity of cytoskeletal regulatory protein Trio is disrupted in neurodevelopmental disorder-related genetic variants,” co-first author, Journal of Biological Chemistry, September 2022. “Mechanism of Trio GEF1 Regulation by Spectrin Repeats,” poster presentation, Cell Symposia: The Biology of Neuropsychiatric Disorders, May 2022. “In vitro fluorescence assay to measure GDP/GTP exchange of guanine nucleotide exchange factors of Rho family GTPases,” co-author, Biology Methods & Protocols, December 2021. “Mechanism of Regulation of TRIO GEF1 activity by Spectrin Repeats,” poster presentation, ASCB 2021 Annual Meeting, 2021. “Calcium(II) oscillations to glucose: An astrocyte relation,” first-author, Biophysical Chemistry, September 2019. “Modeling Perturbations of Baseline Calcium Oscillations and Metabolic Implications in Astrocytes,” presenter, ASBMB 2018 Annual Meeting, April 2018. Education & Credentials Yale University, PhD (2023) Molecular Biophysics & Biochemistry Yale University, Masters (2020) Philosophy Kenyon College, BA (2018) magna cum laude, Biochemistry Admissions U.S. Patent & Trademark Office